Low-Level Laser Therapy for Failed Back Surgery Syndrome: What the Latest Research Shows
- Julian Simpson
- Aug 11
- 3 min read
Low-Level Laser Therapy for Failed Back Surgery Syndrome: What the Latest Research Shows
A breakthrough in chronic post-surgical back pain management

Persistent pain after spinal surgery—known as Failed Back Surgery Syndrome (FBSS)—is one of the most challenging conditions seen in chronic spine care. It affects function, mobility, and quality of life, often leaving patients searching for non-invasive solutions.
A recent clinical study published evaluated the effects of Low-Level Laser Therapy (LLLT) on patients with FBSS, providing strong evidence for its role in reducing pain and disability.
At Healthwise Chiropractic, this type of research is important because it aligns with modern, non-invasive approaches to chronic spinal pain management used in clinical practice across Melbourne and surrounding areas, including Sunbury and Melton.
What is Failed Back Surgery Syndrome?
Failed Back Surgery Syndrome refers to ongoing or recurring low back and/or leg pain following lumbar spine surgery.
Common causes include:
Facet or sacroiliac joint dysfunction
Epidural fibrosis (scar tissue formation)
Disc degeneration or recurrent disc issues
Nerve irritation (including cluneal nerve involvement)
Post-surgical muscle dysfunction
This condition is not rare and is a major driver of long-term disability after spinal surgery.
What did the research study investigate?
This clinical study followed 50 patients with FBSS and examined the effects of Low-Level Laser Therapy (LLLT)applied 3 times per week for 3 weeks.
Treatment targeted:
Lumbar facet joints (L2–S1)
Sacroiliac joints
Cluneal nerve regions
The laser used:
808 nm near-infrared wavelength
500 mW power
20 J/cm² energy density
Key results: measurable pain and disability improvement
The study used two validated clinical measures:
NRS (Numeric Rating Scale) for pain
ODI (Oswestry Disability Index) for functional disability
Pain reduction (NRS scores)
Before treatment: 6.70 ± 1.28
After treatment: 3.26 ± 2.77
6 months later: 3.96 ± 2.74
👉 That represents almost a 50% reduction in pain immediately after treatment, with benefits still present at 6 months.
Disability improvement (ODI scores)
Before treatment: 51.44 ± 16.17
After treatment: 37.62 ± 23.23
6 months later: 41.48 ± 23.04
👉 This shows a significant improvement in functional disability, with sustained benefit over time.
Statistical significance
The results were highly significant:
Pain (NRS): p < 0.001
Disability (ODI): p < 0.001
This means the improvements were not due to chance.
Important clinical insight: age matters
The study also found:
Older patients experienced less improvement compared to younger participants.
This suggests that earlier intervention in chronic post-surgical pain cases may produce better outcomes.
How does Low-Level Laser Therapy work?
Low-Level Laser Therapy works through a process called photobiomodulation.
Key biological effects include:
Improved mitochondrial energy production (ATP)
Reduced inflammatory cytokines (TNF-α, IL-6, IL-1β)
Increased anti-inflammatory cytokines (IL-10, IL-4)
Improved blood flow via nitric oxide release
Reduced oxidative stress and nerve sensitivity
In simple terms:👉 It helps calm inflammation👉 Supports tissue repair👉 Reduces pain signalling👉 Improves functional movement
Why this matters for chronic back pain patients in Melbourne
For patients in Melbourne, Sunbury, and surrounding communities, FBSS often presents as:
Ongoing back pain after surgery
Leg pain or nerve symptoms
Reduced mobility and work capacity
Limited response to medication or passive care
This study supports the growing role of non-invasive, regenerative therapies like LLLT as part of a broader rehabilitation approach.
At Healthwise Chiropractic, these findings reinforce the importance of combining:
Manual therapy
Movement-based rehabilitation
Neuro-musculoskeletal assessment
Evidence-based adjunct therapies like laser therapy
Clinical takeaway
This study concluded:
LLLT significantly reduces pain and disability in FBSS
Improvements can last up to 6 months
Treatment is safe and non-invasive
Best outcomes may occur in younger patients or earlier-stage chronic cases
Final thoughts
Failed Back Surgery Syndrome remains a complex condition, but emerging therapies like Low-Level Laser Therapy offer promising, evidence-based support for patients who have exhausted conventional options.
If you’re experiencing persistent pain after spinal surgery, a structured functional assessment may help identify whether regenerative and conservative therapies could support your recovery.
Reviewed by Dr Julian Simpson, Chiropractor at Health Wise Chiropractic, Sunbury 21 Powellet Street, Sunbury & 131 Wembley Avenue, Strathtulloh
At Health Wise Chiropractic, we regularly treat patients with [condition], helping them return to work, sport, and daily activities pain-free.
reference
Masoumipour M, Barough MS, Jameie SB, Majdabadi A, Hosseinitabatabaei N, Babakhani B. Therapeutic Effects of Low-Level Laser Therapy on Pain and Disability of Patients with Failed Back Surgery Syndrome. Indian J Orthop. 2024 Feb 19;58(4):417-423. doi: 10.1007/s43465-024-01099-2. PMID: 38544539; PMCID: PMC10963664.



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