Laser Therapy for Knee Osteoarthritis: What the Latest Research Shows About Pain Relief and Function
Laser Therapy for Knee Osteoarthritis: What the Latest Research Shows About Pain Relief and Function

A modern, non-invasive approach to knee pain
Knee osteoarthritis is one of the most common causes of chronic joint pain and reduced mobility, particularly in adults over 40. It is a progressive degenerative condition that can significantly affect walking, work capacity, and quality of life.
Recent high-level research published in a systematic review and network meta-analysis (11 randomized controlled trials) has evaluated the effectiveness of laser therapy combined with exercise rehabilitation for knee osteoarthritis.
At Healthwise Chiropractic, this type of evidence is important because it supports modern, non-invasive, movement-based care strategies used for chronic joint pain management across Melbourne, Sunbury, and surrounding communities.
Understanding knee osteoarthritis
Knee osteoarthritis is a progressive condition that leads to:
Joint pain and stiffness
Reduced walking tolerance
Swelling and inflammation
Decline in strength and function
Difficulty with stairs, squatting, and sport
It is one of the leading causes of disability worldwide in adults.
What did the research investigate?
HILT produced more than 2x the pain reduction effect compared to LLLT at 8 weeks.
Functional improvement (WOMAC scores)
At 4 weeks:
LLLT + exercise: SMD = -0.80
HILT + exercise: SMD = -0.91
At 8 weeks:
LLLT + exercise: SMD = -2.92
HILT + exercise: SMD = -2.20
👉 Both treatments significantly improved function, with sustained benefits over time.
Overall clinical takeaway
Across all 11 studies:
Pain improved significantly in both treatment groups
Function improved significantly in both groups
HILT consistently showed stronger long-term effects (8 weeks)
How effective were these treatments overall?
Across the meta-analysis:
Pain reduction occurred in 100% of included studies (VAS improvement)
Functional improvement occurred in all included studies (WOMAC improvement)
Benefits were observed as early as 4 weeks
Stronger effects were seen by 8 weeks
What is laser therapy actually doing?
Both therapies fall under Photobiomodulation therapy, which works by:
Increasing cellular energy production (ATP)
Reducing inflammatory markers
Improving blood flow to joint tissues
Supporting cartilage and soft tissue repair
Decreasing pain signalling pathways
Why HILT may be more effective than LLLT
The research found HILT had stronger outcomes due to:
Deeper tissue penetration
Higher energy delivery
Ability to treat larger joint structures
More sustained biological response
In clinical terms:👉 LLLT = gentle cellular stimulation👉 HILT = deeper, higher-intensity tissue modulation
Why this matters for Melbourne knee pain patients
For patients across Melbourne, Sunbury, and surrounding regions, knee osteoarthritis commonly presents as:
Morning stiffness
Pain with walking or stairs
Reduced sport or exercise tolerance
Progressive loss of knee function
This research supports a key clinical message:
👉 Exercise alone helps👉 But combining exercise with laser therapy significantly improves outcomes
Clinical implications for chiropractic care
At a clinical level, this evidence supports integrating:
Exercise rehabilitation programs
Load management strategies
Joint mobility restoration
Adjunct therapies such as laser therapy
into a broader conservative care plan for knee osteoarthritis.
Reviewed by Dr Julian Simpson, Chiropractor at Health Wise Chiropractic, Sunbury 21 Powellet Street, Sunbury & 131 Wembley Avenue, Strathtulloh
At Health Wise Chiropractic, we regularly treat patients with [condition], helping them return to work, sport, and daily activities pain-free.
reference
Khalilizad M, Hosseinzade D, Marzban Abbas Abadi M. Efficacy of High-Intensity and Low-Level Laser Therapy Combined With Exercise Therapy on Pain and Function in Knee Osteoarthritis: A Systematic Review and Network Meta-analysis. J Lasers Med Sci. 2024 Aug 4;15:e34. doi: 10.34172/jlms.2024.34. PMID: 39193110; PMCID: PMC11348445.



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