Nourishing Solutions for Endometriosis: Exploring the Role of Nutrition
- Julian Simpson
- Nov 8, 2025
- 2 min read
Nourishing Solutions for Endometriosis: Exploring the Role of Nutrition
Endometriosis is a chronic hormone-dependent disease with an inflammatory basis. The prevalence of the disease is around 10% of the general female population, rising to 30–40% of women with dysmenorrhea and up to 50–60% of women with infertility
Symptoms of endometriosis are:
Pelvic Pain
Infertility
Acute abdominal pain
Constipation
Diarrhea
Alternating bowel habits
What is the proposed cause of endometriosis?
Endometrial cells, through retrograde menstruation, reach the pelvis and implant. Inflammation, especially caused by ovulation and menstruation, is central to disease progression. Local inflammation triggered by luteinizing hormone (LH) can cause follicular rupture and may contribute to pelvic lesions.
Exploring the link between nutrition and inflammation - what are the key nutrients to look out for
Polyunsaturated Fatty Acids (PUFAs): Omega-3 fatty acids (e.g., EPA, DHA) have anti-inflammatory properties, while omega-6 fatty acids, found in animal products, are considered pro-inflammatory. Omega-3s have been shown to reduce cardiovascular risk, rheumatoid arthritis, and cancer cachexia
Fibre: Fibre has recognised anti-inflammatory effects [132]. It is fermented by gut microbiota into short-chain fatty acids (SCFAs), which activate immune-regulating pathways, reducing inflammation
What you should avoid
Added Sugars: High consumption of added sugars amplifies pro-inflammatory effects. Elevated blood glucose levels from sugary foods can form advanced glycation end products (AGEs), which trigger oxidative stress, inflammation, and cell death. Food recommendations for people with endometriosis
Practical recommendations suggest that patients with endometriosis may benefit from a diet rich in antioxidants, PUFAs, and vitamins D, C, and E, which have demonstrated anti-inflammatory properties. Avoiding processed foods, red meat, and animal fats could further support symptom management and overall disease control.
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Martire FG, Costantini E, d'Abate C, Capria G, Piccione E, Andreoli A. Endometriosis and Nutrition: Therapeutic Perspectives. J Clin Med. 2025 Jun 5;14(11):3987. doi: 10.3390/jcm14113987. PMID: 40507748; PMCID: PMC12156139.
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