How Fatigue Affects the Spine: What New Research Reveals About Chronic Low Back Pain
- Julian Simpson
- 3 days ago
- 4 min read

How Fatigue Affects the Spine: What New Research Reveals About Chronic Low Back Pain
Chronic low back pain (CLBP) is one of the most common and disabling conditions worldwide, affecting up to 84% of people at some point in their lives. While most of us think of back pain as a simple muscle strain, new research shows that fatigue — both muscular and structural — may play a much deeper role in how the spine functions and degenerates over time.
A recent study from Tongji Hospital in Shanghai has shed light on how fatigue impacts the biomechanics of the lumbar spine, particularly in people with chronic low back pain.
🧠 What They Found
1. Lower Lumbar Segments Are Most Vulnerable
The L4/5 and L5/S1 discs, located near the base of the spine, showed the most significant structural changes in those with chronic low back pain. These discs lost height after fatigue loading — a sign of degeneration and reduced ability to absorb stress.Healthy individuals, on the other hand, maintained stable disc height even after the same level of fatigue.
2. Fatigue Changes How the Spine Bears Load
Both groups showed predictable strain patterns during movement — with tension at the back and compression at the front of the discs during forward bending. However, in the CLBP group, fatigue caused abnormal compression at L5/S1 and reduced the spine’s ability to handle shear strain (the sliding motion between vertebrae).In simpler terms, their spines became “stiffer” and less adaptable under load.
3. Upper Lumbar Segments Stay Stable
Interestingly, the upper spinal segments (L1–L3) remained largely unaffected, suggesting these areas are more resistant to mechanical fatigue and degeneration — possibly due to better joint alignment and muscular support.
💡 What This Means for Back Pain Sufferers
These findings reinforce what many chiropractors observe clinically:
Chronic low back pain often stems from mechanical dysfunction in the lower lumbar spine.
Fatigue — whether from poor posture, prolonged sitting, or repetitive lifting — compounds the issue, creating a vicious cycle of strain, compensation, and further degeneration.
Addressing only muscle tightness or pain may not be enough; we need to restore segmental mobility, balance loading, and build fatigue resistance in the supporting structures.
🧍♂️ The Chiropractic Connection
At Health Wise Chiropractic, we regularly see patients with chronic or recurring low back pain that has developed over months or years. Many of these individuals show classic signs of lumbosacral overload — stiffness at L5/S1, muscular imbalance, and postural fatigue.
Chiropractic care can play a key role in:
Improving spinal motion at the L4–S1 junction.We do this by assessing your posture , as an altered curve in your lower back can put extra pressure at this junction.
Reducing mechanical compression through targeted adjustments.
Enhancing muscular endurance and coordination, preventing fatigue-induced dysfunction.
Educating patients on posture, lifting mechanics, and recovery strategies to protect spinal discs long-term.
⚙️ Takeaway
This research highlights a crucial point:
Fatigue isn’t just a feeling — it’s a mechanical event that can alter the way your spine functions.
When the lower lumbar discs lose their ability to dissipate strain, they become prone to injury and degeneration, fueling the chronic pain cycle.By addressing fatigue, mobility, and spinal alignment together, chiropractic care provides a proactive way to protect the lower back and restore healthy spinal movement.
Low Back Pain Chiropractor
Q: How does chiropractic care help with lower back pain?Chiropractors address spinal misalignments, muscle tension, and posture issues that often cause or worsen back pain.
Q: Is chiropractic safe for chronic back pain?Yes, chiropractic care is a safe and natural approach for managing both acute and chronic back pain without relying solely on medication.
Q: How many sessions will I need for back pain?It depends on the severity. Some patients feel relief in just a few visits, while others need ongoing care.
Q: Can chiropractic prevent future back pain?Yes, with posture correction, strengthening exercises, and regular spinal care, chiropractic can help reduce the risk of recurrence.
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Xi X, Jia L, Yu W, Yu H, Qin Y, Tsai TY, Yu Y, Cheng L. Fatigue-induced biomechanical decoupling at L4-S1 discs: mechanism of disc degeneration in chronic low back pain. BMC Musculoskelet Disord. 2025 Oct 27;26(1):1001. doi: 10.1186/s12891-025-09238-y. PMID: 41146101; PMCID: PMC12560559.



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