Characteristics of the nerve barrier and the blood dorsal root ganglion barrier in health/ disease

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Both blood nerve barrier (BNB) and blood DRG barrier (BDB) are crucial in maintaining homeostasis of the peripheral nerve.

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Tight junction proteins have distinct localization and functions in these barriers.

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Neuropathies of different etiologies involve breakdown of BNB and/or BDB.

Reference

Review Article Characteristics of the nerve barrier and the blood dorsal root ganglion barrier in health and disease

Author links open overlay panelA.K.ReinholdH.L.Rittner